Zocor simvastatin dosing, indications, interactions. Common side effects include constipation, headaches, and nausea. Serious side effects may include muscle breakdown, liver problems, and increased blood sugar levels. Take simvastatin oral suspension liquid on an empty stomach. Simvastatin 10 mg tablets simvastatin zocor is a prescription drug approved to treat high cholesterol and high triglycerides. Adult dosage ages 18 years and older typical starting dosage. Contact your doctor if you have severe side effects of zocor including. Simvastatin side effects, dosage, usage, and more healthline. Some side effects of simvastatin may occur that usually do not need medical attention. Dizziness fainting fast or irregular heartbeat less common. Our zocor simvastatin side effects drug center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Raff on what are the side effects of simvastatin 20 mg. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Possible side effects like all medicines, simvastatin tablets may occasionally cause side effects in some patients. The benefits and risks of using aspen simvastatin concomitantly with immunosuppressants, fibrates or lipidlowering doses of niacin should be carefully considered, and the dose of aspen simvastatin should generally not exceed 10 mg day. Keep taking simvastatin unless your doctor tells you to stop. Following a physical, you might be planning to take a statin. Mood, personality, and behavior changes during treatment with. There is evidence of harm to unborn babies when taken during pregnancy and it should not be used by those who are breastfeeding. The usual starting dose for children 10 17 years old is 10 mg. This is not a complete list of side effects and others may occur. Simvastatin oral tablet doesnt drowsiness, but it can cause other side effects. Side effects of simvastatin oral suspension, warnings, uses. Articles from the british journal of general practice are provided here courtesy of royal college of general practitioners.
Comparative efficacy and tolerability of 5 and 10 mg. Tell your doctor if you notice that any of these side effects worsen, will not go away, or worry you while taking simvastatin. In case of any doubt consult your doctor or pharmacist. The fda warnings regarding usage of a higher dosage of simvastatin 80 mg and limitations of using this medication with drugs such as calcium channel blockers for example amlodipine have been reducing the. This medicine may help prevent medical problems eg, heart attacks. Simvastatin zocor works best if you take it in the evening since your body makes most of its cholesterol at night. Simvastatin 40mg tablets summary of product characteristics. What are the side effects of simvastatin 40mg does it help.
Usually, the starting dose is 10 or 20 mg once a day, in the evening. Many people using this medication do not have serious side effects. The information here is sourced well and enriched with great visual photo and video illustrations. Side effects can be mild or severe, temporary or permanent. Problems resolved with drug discontinuation and recurred with. You can also call a poison help hotline for directions on what to do. Doctors give trusted answers on uses, effects, side effects, and cautions. An overdose of simvastatin is not considered to be life threatening, but to be safe, get help. Do not take more than 10 mg of simvastatin with diltiazem or verapamil, or more. The usual starting dose is 10mg taken in the evening. It is a key member of the statin drugs and it is normally marketed under the names simlup, zocor and simvacor among others. However, its most serious form, rhabdomyolysis, is a very rare side effect.
If you are at high risk of heart disease, the starting dose is. Effects of simvastatin 40 mg daily on muscle and liver. Pregnancy must be avoided while on simvastatin due to potentially severe birth defects. Seek help immediately if you experience any of these serious side effects while taking simvastatin. Call your doctor for medical advice about side effects. The brickred coloured, ovalshaped, biconvex, filmcoated. The average daily dose for most people taking this medication is 5 mg to 40 mg a day. If after 2 months the simvastatin 20 mg dose is tolerated, the dose of simvastatin will be increased to 40 mg each evening by mouth. Read the side effects of simvastatin as described in the medical literature. Learn about the reported side effects, related class drugs, and how these medications will affect your daily lifestyle. Side effects of zocor simvastatin, warnings, uses rxlist. If you notice any of the following rare but serious side effects, tell your doctor immediately.
Simvastatin is contraindicated with pregnancy, breastfeeding, and liver disease. The efficacy of 10 mg simvastatin in lowering these lipid parameters was also superior 19 vs. Coadministration with amiodarone, amlodipine, or ranolazine. In patients taking amiodarone, amlodipine, verapamil or diltiazem concomitantly with simvastatin, the dose of simvastatin should not exceed 20 mg day. Learn about side effects, drug interactions, dosages, warnings, and more. Jul 10, 2009 simvastatin 40mgs is the standard dose of the standardly chosen statin used to lower cholesterol in the uk. These side effects may go away during treatment as your body adjusts to the medicine. This may include dizziness,confusion,depression difficulty breathing etc. Safety of simvastatin in lam and tsc full text view. The effects of ezetimibesimvastatin 1020 mg versus. In the heart protection study, involving 20,536 patients age range 4080 years, 25% women, 97% caucasians, 3% other races treated with simvastatin 40 mgday n10,269 or placebo n10,267 over a mean of 5 years, only serious adverse reactions and discontinuations due to any adverse reactions were recorded discontinuation rates due to adverse. Reduce simvastatin dose by 50%, and do not exceed 20 mg day or 40 mg day in those previously tolerating 80 mg day when initiating lomitapide. May, 2020 effects of simvastatin 40 mg daily on muscle and liver adverse effects in a 5year randomized placebocontrolled trial in 20,536 highrisk people. Patients cannot breastfeed while on simvastatin due to potentially disrupting the infants lipid metabolism.
Simvastatin has a much broader range of interactions with other medications compared to newer statins such as atorvastatin and rosuvastatin. Simvastatin is a kind of medication that is mainly used for controlling elevated cholesterol. If you think you may have taken an overdose, or too much simvastatin, it is important you seek emergency medical treatment. Dec 11, 2014 myopathy is a known side effect of all statins, including simvastatin, and the risk increases with higher doses. When you find the article helpful, feel free to share it with your friends or colleagues. A side effect is an unwanted response to a medication when it is taken in normal doses. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Shake the liquid for at least 20 seconds before you measure a dose. The more common side effects that can occur with simvastatin include. Bladder pain bloody or cloudy urine blurred vision body aches or pain chills cough darkcolored urine difficult, burning, or painful urination difficulty with breathing.
Simvastatin oral tablet 10mg drug medication dosage information. Check with your doctor immediately if any of the following side effects occur. What are the side effects of simvastatin 20 mg answers on. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is.
May 09, 2016 simvastatin oral suspension is an hmgcoa reductase inhibitor statin indicated as an adjunctive therapy to diet to. You may need to take simvastatin on a longterm basis. Simvastatin is used together with diet to lower blood levels of bad cholesterol lowdensity lipoprotein, or ldl, to increase levels of good cholesterol highdensity lipoprotein, or hdl, and to lower triglycerides a type of fat in the blood simvastatin is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart. You can also buy a lowstrength 10mg tablet from a pharmacy. Hello, we provide concise yet detailed articles on effect choices.
Sometimes, taking a combination of cholesterol drugs can provide the same result with lower doses of statins. Possible sleepiness and lack of coordination as well as the discomfort of the insertion itself which should be mild. A very serious allergic reaction to this drug is rare. The first month i had side effects of leg cramps, toe numbness and muscle weakness in legs so consulted with doc and she recommended taking every other day. Sixtyfour patients with ischemic heart disease treated with simvastatin 20 mg who had not a chieved the. Jun 08, 2011 the highest approved dose of simvastatin 80 mg should be used only in those patients who have already been taking it for at least 12 months without signs of myopathy, the fda announced wednesday. By decreasing these levels, you can also reduce your risk of developing problems related to high cholesterol, such as heart disease or a heart attack. If youre driving a little over the speed limit, it slightly increases your risk of a crash. The tan coloured, ovalshaped, biconvex, filmcoated tablets marked 20 on one side and breakline on the other side contain 20mg simvastatin. Simvastatin 10 mg side effects of simvastatin 10 mg. Use the dosing syringe provided, or use a medicine dosemeasuring device not a kitchen spoon. The effects of ezetimibesimvastatin 1020 mg versus simvastatin 40 mg in high cholesterol and coronary heart disease study p04039am2completed the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. You can learn about them and what your chances are of getting them by following the link above.
I f any of the following serious side effects happen, stop taking the medicine and tell your doctor immediately or go to the emergency room at your nearest hospital. Simvastatin is usually taken in the evening or at bedtime. The usual dose range for adults is between 10 40 mg once daily, usually taken with the evening meal. A lower dose may be needed in people with kidney problems. We usually begin at 10 mg once daily, and measure fasting lipid levels within 4 weeks and adjust dosage according to the response. Our simvastatin oral suspension side effects drug center provides a comprehensive view of available drug information on the potential side effects when taking this medication. In patients taking simvastatin concomitantly with fibrates other than gemfibrozil see section 4. Side effects not requiring immediate medical attention. Sep 07, 2012 simvastatin 40 mg side effects worried about the side effects you might get from the 40mg simvastatin. For the most part side effects have been mild and shortlived. Jan 17, 2019 our zocor simvastatin side effects drug center provides a comprehensive view of available drug information on the potential side effects when taking this medication. The usual maximum dose for this medication is 40 milligrams a day. Avoid grapefruit and grapefruit juice while taking this medicine because it can increase the amount of medication in your body, which increases your risk of side effects.
Most patients tolerate it well, but like all drugs it can have side effects. A very small number of people taking simvastatin may have mild memory problems or confusion. Fda warns against use of highdose simvastatin medpage today. Your condition will not improve any faster, and the risk of serious side effects may be. The following side effects were reported rarely between 1 in and 1 in 10,000 people are likely to be affected. The childs healthcare provider may increase this dosage to a maximum of 40 mg daily if necessary. Pdf the combination of nutraceutical and simvastatin. May 1, 2011, harri daniel, comments off on benefits of simvastatin. Doses may be adjusted as needed, should the participant experience side effects from simvastatin. For children ages 10 to 17, the recommended starting simvastatin dosage is 10 mg once a day. Zocor tablets are supplied as 5, 10, 20, 40 or 80 mg tablets. Sibelium 10 mg tablet side effects answers on healthtap. Coadministration with dronedarone, verapamil, or diltiazem. The side effects listed below are not experienced by everyone who takes this medication.